Essential Tremor (ET) is the most common movement disorder and causes progressively disabling rhythmic trembling of the hands, head, voice, legs or trunk. ET affects an estimated 10 million Americans of all ages and millions more worldwide. ET is commonly viewed as a relatively benign disease, however, it is a major source of disability and social isolation for patients who suffer with severe tremors. The disabling aspects of ET, like significant hand tremors, can impair patients’ ability to eat, groom, write, perform household activities, and function in the workplace.
There is low public awareness and a tremendous need for new, safe and effective treatments for ET. Up to 50% of people with ET report lack of efficacy from oral prescription medication and up to one-third who respond discontinue therapy due to side-effects. By modulating the brain’s abnormal neural activity, CX-8998 may offer new hope to patients, significantly improving quality of life without compromising side effects.
People with Essential Tremor (ET) and their families do not need to suffer alone. There are several organizations that provide hope to the ET community through awareness, education, support and research.